1429494-65-4

Upstream product

• 622847-77-2 2-(4-oxo-3,4-dihydro-2-quinazolinyl)-2-(tetrahydro-2-furanylidene)acetonitrile 
• 103-49-1 dibenzylamine 
• 100-46-9 benzylamine 
• 307533-51-3 C₁₄H₁₂ClN₃O₂ 

Relevant academic research and scientific papers

Synthesis of 2-(2-hetaryl)-6-hydroxy-3-(R-amino)-2-hexenenitriles

The reaction of 2-hetaryl-2-(tetrahydrofuran-2-ylidene)acetonitriles and 6-chloro-2-(2-hetarylidene)-3-oxohexanenitriles with amines was studied. It was shown that the reaction of primary aliphatic amines with 6-chloro-2-(2- hetarylidene)-3-oxohexanenitriles takes place through a stage involving the formation of 2-hetaryl-2-(tetrahydrofuran-2-ylidene)acetonitriles followed by opening of the furanylidene fragment of the latter and the formation of 2-(2-hetaryl)-6-hydroxy-3-(R-amino)-2-hexenenitriles.