1429501-86-9

Upstream product

• 1429501-83-6 5-(2-(benzyl(6-(2,2-difluoro-2-phenylethoxy)hexyl)amino)acetyl)-8-(benzyloxy)-quinolin-2(1H)-one hydrochloride salt 
• 1429501-81-4 5-(2-(benzyl(6-(2,2-difluoro-2-phenylethoxy)hexyl)amino)acetyl)-8-(benzyloxy)-quinolin-2(1H)-one 
• 100-46-9 benzylamine 
• 915132-91-1 N-benzyl-6-(2,2-difluoro-(2-phenyl)ethoxy)hexane-1-amine 
• 915133-34-5 N-benzyl-6-(2,2-difluoro-(2-phenyl)ethoxy)hexane-1-amine 

Relevant academic research and scientific papers

Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.

The present invention is concerned with a compound of formula (Ap) or a pharmaceutically acceptable salt thereof, wherein P1 represents a hydroxy protecting group and P3 represents an amino protecting group. The present invention is also related to a process for preparing a compound of formula (I) or any pharmaceutically acceptable salt thereof, via a novel intermediate compound (Ap).

PROCESS FOR PREPARING 5-(2-{[6-(2,2-DIFLUORO-2-PHENYLETHOXY)HEXYL]AMINO}-1(R)-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE VIA A NOVEL INTERMEDIATE

The present invention is concerned with a process for preparing a 5-(2-{[6-(2,2-difl 2-phenylethoxy) hexyl]amino}-1 (R)-hydroxyethyl)-8-hydroxyquinolin-2(1 H)-one compound of formula (I) or a pharmaceutically acceptable salt thereof.