1429656-34-7Relevant academic research and scientific papers
Synthetic route to chiral indolines via ring-opening/C-N cyclization of activated 2-haloarylaziridines
Ghorai, Manas K.,Nanaji
, p. 3867 - 3878 (2013/06/05)
A practical approach for the synthesis of 3-substituted indolines via regio- and stereoselective SN2-type ring-opening of 2-(2-halophenyl)-N-tosylaziridines with heteroatomic nucleophiles (O, N, and S) followed by palladium-catalyzed intramolecular C-N cyclization is reported in excellent yields (up to >99%) and enantiomeric excess (ee 99%).
