142976-37-2

Basic information

• Product Name: (1R,4S,4aS)-6,7-Dimethoxy-4-methyl-1-(4-nitro-phenyl)-4,4a,9,10-tetrahydro-3H-2-oxa-10a-aza-phenanthrene
• CAS NO: 142976-37-2
• Molecular Weight: 384.432
• Mol File: 142976-37-2.mol

Chemical Properties

• CAS DataBase Reference: (1R,4S,4aS)-6,7-Dimethoxy-4-methyl-1-(4-nitro-phenyl)-4,4a,9,10-tetrahydro-3H-2-oxa-10a-aza-phenanthrene(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,4S,4aS)-6,7-Dimethoxy-4-methyl-1-(4-nitro-phenyl)-4,4a,9,10-tetrahydro-3H-2-oxa-10a-aza-phenanthrene(142976-37-2)
• EPA Substance Registry System: (1R,4S,4aS)-6,7-Dimethoxy-4-methyl-1-(4-nitro-phenyl)-4,4a,9,10-tetrahydro-3H-2-oxa-10a-aza-phenanthrene(142976-37-2)

Safety Data

• Hazardous Substances Data: 142976-37-2(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 21271-06-7 (1R*,1'R*)-1-(1'-methyl-2'-hydroxyethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 21271-06-7 erythro-1-<1'-(hydroxymethyl)-ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Synthesis and Conformational Analysis of Stereoisomeric 1- and 2-Methyl-2H,4H-1,6,7,11b-tetrahydro-1,3-oxazinoisoquinolines

Starting from diastereomerically pure 1-(β-hydroxyethyl)-1'-methyl- or 2'-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines (3a,b and 5a,b), 4-unsubstituted, 4-p-nitrophenyl- and 4-oxo-1- or 2-methyl-9,10-dimethoxy-2H,4H-1,6,7,11b-tetrahydro-1,3-oxazinoisoquinoline diastereomers (a and b) 6-9, 12 and 13 were prepared.The relative configurations and the predominant conformations were determined by 1H and 13C NMR spectroscopy, use also being made of DR, DEPT, DNOE and 2D-HSC measurements.