142976-38-3

Upstream product

• 52156-11-3 1-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)propan-2-one 
• 17394-91-1 1-(6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-propan-2-one; hydrochloride 
• 555-16-8 4-nitrobenzaldehdye 
• 101776-94-7 (1R^*,2'R^*)-1-(2'-Hydroxypropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 101776-94-7 (1R^*,2'S^*)-1-(2'-Hydroxypropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Synthesis and Conformational Analysis of Stereoisomeric 1- and 2-Methyl-2H,4H-1,6,7,11b-tetrahydro-1,3-oxazinoisoquinolines

Starting from diastereomerically pure 1-(β-hydroxyethyl)-1'-methyl- or 2'-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines (3a,b and 5a,b), 4-unsubstituted, 4-p-nitrophenyl- and 4-oxo-1- or 2-methyl-9,10-dimethoxy-2H,4H-1,6,7,11b-tetrahydro-1,3-oxazinoisoquinoline diastereomers (a and b) 6-9, 12 and 13 were prepared.The relative configurations and the predominant conformations were determined by 1H and 13C NMR spectroscopy, use also being made of DR, DEPT, DNOE and 2D-HSC measurements.