142979-95-1

Basic information

• Product Name: 5,5-bis[(phenylsulfanyl)methyl]imidazolidine-2,4-dione
• Synonyms: 2,4-imidazolidinedione, 5,5-bis[(phenylthio)methyl]-; 5,5-Bis((phenylthio)methyl)-2,4-imidazolidinedione; 5,5-Bis[(phenylthio)methyl]-2,4-imidazolidinedione
• CAS NO: 142979-95-1
• Molecular Formula: C₁₇H₁₆N₂O₂S₂
• Molecular Weight: 344.4511
• Mol File: 142979-95-1.mol
• Article Data: 1

Chemical Properties

• Density: 1.37g/cm³
• Refractive Index: 1.692
• CAS DataBase Reference: 5,5-bis[(phenylsulfanyl)methyl]imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-bis[(phenylsulfanyl)methyl]imidazolidine-2,4-dione(142979-95-1)
• EPA Substance Registry System: 5,5-bis[(phenylsulfanyl)methyl]imidazolidine-2,4-dione(142979-95-1)

Safety Data

• Hazardous Substances Data: 142979-95-1(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 35737-59-8 1,3-bis(phenylthio)propan-2-one 
• 151-50-8 potassium cyanide 
• 506-87-6 ammonium carbonate 

Relevant articles and documents

5,5-Disubstituted Hydantoins: Syntheses and Anti-HIV Activity

A series of 5,5-disubstituted hydantoin derivatives was synthesized by alkylating 5,5-bis(mercaptomethyl)-2,4-imidazolidinedione (3) with various halomethylaromatic or halomethylheteroaromatic precursors, or by using the Buchener-Berg procedure on the required ketone.When evaluated for their ability to inhibit HIV-induced cell killing and virus production in CEM or MT-2 cells only compounds 2, 4n, 4o, and 4i demonstrated modest activity, the latter with an IC50 = 53 μM