142995-02-6 Usage
Benzothiophene derivative
A compound that is derived from benzothiophene, which is a five-membered heterocyclic aromatic ring containing a sulfur atom.
Cyclohexylcarbonylamine functional group
A specific functional group present in the compound, consisting of a cyclohexyl ring (a six-membered ring with carbon atoms) attached to an amide group (a carbonyl group connected to a nitrogen atom with a single bond).
Pharmaceutical applications
The potential use of this compound in the development of medications, due to its unique molecular structure and properties.
Biological activities
The possible effects that the compound may have on biological systems, which could be relevant for its pharmaceutical applications.
Medicinal chemistry research and development
The process of studying and developing new compounds, like 2-[(cyclohexylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, for potential therapeutic use in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142995-02-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,9,9 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142995-02:
(8*1)+(7*4)+(6*2)+(5*9)+(4*9)+(3*5)+(2*0)+(1*2)=146
146 % 10 = 6
So 142995-02-6 is a valid CAS Registry Number.
142995-02-6Relevant articles and documents
Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3
Patch, Raymond J.,Baumann, Christian A.,Liu, Jian,Gibbs, Alan C.,Ott, Heidi,Lattanze, Jennifer,Player, Mark R.
, p. 3282 - 3286 (2007/10/03)
A series of 2-acylaminothiophene-3-carboxamides has been identified which exhibit potent inhibitory activity against the FLT3 tyrosine kinase. Compound 44 inhibits the isolated enzyme (IC50 = 0.027 μM) and blocks the proliferation of MV4-11 cel