Welcome to LookChem.com Sign In|Join Free
  • or

143-67-9

Post Buying Request

143-67-9 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Vinblastine sulfate
Cas No: 143-67-9
No Data No Data No Data TAIZHOU SHASIN PHARMACHEM CO.,LTD Contact Supplier
Vinblastine sulfate Manufacturer/High quality/Best price/In stock
Cas No: 143-67-9
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High purity Vinblastine sulfate with high quality and best price cas:143-67-9
Cas No: 143-67-9
USD $ 110.0-250.0 / Gram 1 Gram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
143-67-9 Vinblastine sulfate
Cas No: 143-67-9
USD $ 2.0-2.0 / Kilogram 1 Kilogram 100 Metric Ton/Year Hebei yanxi chemical co.,LTD. Contact Supplier
High quality Vinblastine Sulfate
Cas No: 143-67-9
USD $ 800.0-1000.0 / Kilogram 1 Kilogram 5000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
High quality Vinblastine Sulphate supplier in China
Cas No: 143-67-9
No Data No Data No Data Simagchem Corporation Contact Supplier
Vinblastine sulfate
Cas No: 143-67-9
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Vinblastine Sulphate /143-67-9
Cas No: 143-67-9
USD $ 1.0-1.0 / Kilogram 1 Kilogram 800 Kilogram/Week Henan Sinotech Import&Export Corporation Contact Supplier
Vinblastine sulfate
Cas No: 143-67-9
No Data 1 Kilogram 10 Kilogram/Day HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
Chinese Vinblastine sulfate supplier/suppliers manufacturer factory
Cas No: 143-67-9
No Data No Data 1000 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier

143-67-9 Usage

Chemical Properties

Crystalline Solid

Biological Activity

Anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells.

Fire Hazard

Flash point data for Vinblastine sulfate are not available; however Vinblastine sulfate is probably combustible.

Uses

antineoplastic, spindle poison

Uses

Labelled Vinblastine (V314000). Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic.

General Description

An anticancer drug. White to slightly yellow crystalline powder.

Health Hazard

SYMPTOMS: Symptoms of exposure to Vinblastine sulfate include temporary mental depression, paresthesias, loss of deep-tendon reflexes, headache, convulsions, psychoses; dysfunction of the autonomic nervous system, with marked constipation, paralytic ileus, urinary retention, bilateral pain and tenderness of the parotid glands associated with dryness of the mouth, sinus tachycardia; nausea, vomiting, anorexia, diarrhea; loss of hair, vesicular mucositis of the mouth, and dermatitis.

Brand name

Velban (Lilly).

Air & Water Reactions

Water soluble..Rapidly hydrolyzes.

Purification Methods

Crystallise the sulfate from MeOH or EtOH and dry it in vacuo over conc H2SO4. The free base crystallises from EtOH or MeOH m 211-216o (+ 2MeOH .1 H2O) and forms a stable etherate from Et2O with m 201-211o, and [] D +42o (CHCl3), and UV max at 214 and 259nm (log  4.73 and 4.21). The dihydrochloride has m 244-246o(dec)(MeOH). It is a monoamine oxidase B inhibitor and induces microtubule aggregation. It is an antineoplastic drug for Hodgkin’s lymphoma. [Neuss et al. J Am Chem Soc 81 4754 1959, Jong-KeunSon et al. J Med Chem 33 1845 1990, Warfield & Bouck Science 186 1219 1974, Beilstein 26 III/IV 3167.]

Reactivity Profile

Vinblastine sulfate is sensitive to light, hydrolysis, oxidation, and heat. Vinblastine sulfate is very hygroscopic. .
InChI:InChI=1/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28?,37-,38+,39+,42-,43+,44+,45-,46-;/m0./s1

143-67-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1713004)  Vinblastine sulfate  United States Pharmacopeia (USP) Reference Standard 143-67-9 1713004-50MG 10,547.55CNY Detail

143-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name vincaleukoblastine sulfate

1.2 Other means of identification

Product number -
Other names (+)-vinblastine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143-67-9 SDS

143-67-9Downstream Products

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields