14300-33-5

Basic information

• Product Name: DICYCLOPROPYLMETHANOL
• Synonyms: Cyclopropanemethanol, alpha-cyclopropyl-;DCPM-OH;DICYCLOPROPYL CARBINOL;DICYCLOPROPYLMETHANOL;Biscyclopropylmethanol;Dicyclopropylmethyl alcohol;Einecs 238-236-3;Dicyclopropyl carbinol 97%
• CAS NO: 14300-33-5
• Molecular Formula: C₇H₁₂O
• Molecular Weight: 112.17
• EINECS: 238-236-3
• Mol File: 14300-33-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 69 °C13 mm Hg(lit.)
• Flash Point: >110°C
• Appearance: /
• Density: 0.951 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.357mmHg at 25°C
• Refractive Index: n20/D 1.464
• Storage Temp.: 2-8°C
• PKA: 15.04±0.20(Predicted)
• Water Solubility: Sparingly soluble in water.
• BRN: 2203215
• CAS DataBase Reference: DICYCLOPROPYLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: DICYCLOPROPYLMETHANOL(14300-33-5)
• EPA Substance Registry System: DICYCLOPROPYLMETHANOL(14300-33-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 14300-33-5(Hazardous Substances Data)

Usage

Uses

Dicyclopropylmethanol is used as protecting group reagent for carboxylic acids; the formed esters are very mildly and selectively cleaved.

InChI:InChI=1/C7H12O/c8-7(5-1-2-5)6-3-4-6/h5-8H,1-4H2

Upstream product

• 1121-37-5 dicyclopropyl ketone 
• 23719-80-4 cyclopropylmagnesium bromide 
• 1489-69-6 Cyclopropanecarboxaldehyde 

Downstream Products

• 802911-34-8 (2S,3S)-2-((2S,3R)-2-Amino-3-phenyl-butyrylamino)-3-methyl-pentanoic acid dicyclopropylmethyl ester 
• 802911-33-7 (2S,3S)-2-((2S,3R)-2-Benzyloxycarbonylamino-3-phenyl-butyrylamino)-3-methyl-pentanoic acid dicyclopropylmethyl ester 
• 1154472-19-1 4-benzyl-8-(1-dicyclopropylmethoxy)-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine 
• 118285-30-6 (dicyclopropylmethoxy)acetic acid ethyl ester 
• 23772-96-5 1,2-Dicyclopropyl-2-phenylaethylen 
• 13375-29-6 dicyclopropylmethylamine 
• 7327-86-8 Dicyclopropylketone (2,4-dinitrophenyl)hydrazone 

Relevant articles and documents

-

-

CaSR ANTAGONIST

The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the description.

REACTION OF DICYCLOPROPYL KETONE WITH LiAlH4 AND TiCl4

-