143003-64-9Relevant academic research and scientific papers
Diastereofacial selectivity in the aldol reactions of chiral α-methyl aldehydes: A computer modelling approach
Gennari, Cesare,Vieth, Siegfried,Comotti, Angiolina,Vulpetti, Anna,Goodman, Jonathan M.,Paterson, Ian
, p. 4439 - 4458 (2007/10/02)
Transition state modelling of the aldol reaction of Z enol borinates with chiral α-methyl aldehydes (see Schemes 4 and 6) suggests that three transition structures (F, AF, R) play a dominant role in controlling π-facial selectivity. The "Felkin" structure
