143006-63-7

Basic information

• Product Name: (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-3-hydroxy-2-benzylpropyl)-2,2-dimethyl-1,3-oxazolidine
• Synonyms: (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-3-hydroxy-2-benzylpropyl)-2,2-dimethyl-1,3-oxazolidine
• CAS NO: 143006-63-7
• Molecular Weight: 439.595
• Mol File: 143006-63-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-3-hydroxy-2-benzylpropyl)-2,2-dimethyl-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-3-hydroxy-2-benzylpropyl)-2,2-dimethyl-1,3-oxazolidine(143006-63-7)
• EPA Substance Registry System: (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-3-hydroxy-2-benzylpropyl)-2,2-dimethyl-1,3-oxazolidine(143006-63-7)

Safety Data

• Hazardous Substances Data: 143006-63-7(Hazardous Substances Data)

Upstream product

• 143006-57-9 (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-(2-(iodomethyl)-3-propenyl)-2,2-dimethyl-1,3-oxazolidine 
• 143006-56-8 (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-(2-(chloromethyl)-3-propenyl)-2,2-dimethyl-1,3-oxazolidine 
• 143006-54-6 (4S,5S)-5-((tert-butoxycarbonyl)amino)-2-(chloromethyl)-6-phenyl-1-hexen-4-ol 
• 143006-60-4 (4S,5S)-4-benzyl-5-(2-benzyl-3-propenyl)-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidine 

Downstream Products

• 1026816-34-1 (4S,5S)-4-Benzyl-5-((R)-2-benzylcarbamoyl-3-phenyl-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 126409-25-4 (2R,4S,5S)-N,2-dibenzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanamide 
• 143006-64-8 (4S,5S)-4-benzyl-3-(tert-butoxycarbonyl)-5-((2R)-2-carboxy-3-phenylpropyl)-2,2-dimethyl-1,3-oxazolidine 

Relevant articles and documents

Allyltrichlorostannane additions to α-amino aldehydes: Application to the total synthesis of the aspartyl protease inhibitors L-682,679, L-684,414, L-685,434, and L-685,458

The hydroxyethylene dipeptide isosteres L-682,679, L-684,414, L-685,434, and L-685,458 were synthesized in a few steps by a sequence involving an allyltrichlorostannane coupling with an α-amino aldehyde, followed by hydroboration of the corresponding 1,2-