14301-14-5

Upstream product

• 7317-52-4 2,3,4,5-tetraphenyl-2-cyclopenten-1-one 
• 133358-05-1 C₃₂H₁₈Cl₂O₄ 
• 133376-69-9 1,4-diphenyltriphenylene-2,3-diolcarbonate 
• 133357-95-6 1,4-diphenyltriphenylene-2,3-diol 
• 5660-91-3 1,3-diphenyl-2H-cyclopenta<1>phenanthren-2-one 
• 2510-55-6 9-cyanophenanthrene 
• 501-65-5 diphenyl acetylene 
• 172878-79-4 10-iodophenanthrene-9-carbonitrile 

Relevant academic research and scientific papers

Carbopalladation of nitriles: Synthesis of 2,3-diarylindenones and polycyclic aromatic ketones by the Pd-catalyzed annulation of alkynes and bicyclic alkenes by 2-iodoarenenitriles

2-Iodobenzonitrile, its derivatives, and various heterocyclic analogues undergo palladium(O)-catalyzed annulation onto diarylacetylenes or bicyclic alkenes to afford 2,3-diarylindenones and polycyclic aromatic ketones in very good to excellent yields. This reaction represents one of the first examples of the addition of an organopalladium moiety to the carbon-nitrogen triple bond of a nitrile. The reaction is compatible with a number of functional groups. A reaction mechanism, as well as a model accounting for the electronic effects of substituents on the aromatic ring of the nitrile, is proposed.

1,4-Di-o-tolyl-2,3-naphthoquinone

1,4-Di-o-tolyl-2,3-naphthoquinone 1, produced by lead tetraacetate oxidation of 2,3-dihydroxy-1,4-di-o-tolylnaphthalene 2 at -30 deg C, is sufficiently stable to allow purification involving aqueous work-up and low temperature chromatography.It has been c