1430118-99-2Relevant academic research and scientific papers
Pd-Catalyzed Stereoselective Carboperfluoroalkylation of Alkynes
Li, Zhaodong,García-Domínguez, Andrés,Nevado, Cristina
, p. 11610 - 11613 (2015)
A Pd-catalyzed three component reaction involving terminal alkynes, boronic acids, and perfluoroalkyl iodides is presented here. Trisubstituted perfluoroalkenes can be obtained in a highly regio- and stereocontrolled manner by the simultaneous addition of both aryl and CnFm groups across the triple bond in a radical-mediated process. The reaction is operationally simple offering a broad scope and functional group tolerance.
Reactions of trifluoromethyl-substituted arylacetylenes with arenes in superacids
Alkhafaji,Ryabukhin,Muzalevskiy,Osetrova,Vasilyev,Nenajdenko
, p. 327 - 341 (2013/07/26)
Protonation of the C≡C bond in trifluoromethyl-substituted arylacetylenes ArC≡CCF3 by the action of superacids (CF 3SO3H or HSO3F) generates vinyl cations ArC+=CHCF3 which react with arenes Ar′H to give alkenes Ar(Ar′)C=CHCF3. Protonation of the latter at the C=C bond in the reaction medium yields stable cations Ar(Ar′)C +-CH2CF3 which are converted into E/Z-isomeric alkenes Ar(Ar′)C=CHCF3 and/or alcohols Ar(Ar′)C(OH) CH2CF3 as a result of quenching of superacid reaction solution.
