143059-83-0

Basic information

• Product Name: (4R,5S)-3-((1S,2R)-2-Fluoro-cyclopropyl)-4,5-diphenyl-oxazolidin-2-one
• CAS NO: 143059-83-0
• Molecular Weight: 297.329
• Mol File: 143059-83-0.mol

Chemical Properties

• CAS DataBase Reference: (4R,5S)-3-((1S,2R)-2-Fluoro-cyclopropyl)-4,5-diphenyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-3-((1S,2R)-2-Fluoro-cyclopropyl)-4,5-diphenyl-oxazolidin-2-one(143059-83-0)
• EPA Substance Registry System: (4R,5S)-3-((1S,2R)-2-Fluoro-cyclopropyl)-4,5-diphenyl-oxazolidin-2-one(143059-83-0)

Safety Data

• Hazardous Substances Data: 143059-83-0(Hazardous Substances Data)

Upstream product

• 1493-01-2 fluorodiiodomethane 
• 143059-81-8 (4R,5S)-4,5-diphenyl-3-vinyloxazolidin-2-one 

Relevant articles and documents

Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine, the Key Intermediate of the New Generation of Quinolonecarboxylic Acid, DU-6859

The title synthesis was achieved by featuring diastereoface selective cyclopropanation of (4R,5S)-4,5-diphenyl-3-vinyl-2-oxazolidinone, the chiral and conformationally rigid N-vinylcarbamate, with zincmonofluorocarbenoid followed by hydrogenolysis of form

Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine

The title synthesis was achieved by featuring diastereoface-selective cyclopropanation of (4R,5S)-4,5-diphenyl-3-vinyl-2-oxazolidinone and its related compounds, the chiral conformationally rigid N-vinylcarbamates, with zinc-monofluorocarbenoid, followed