143060-10-0Relevant articles and documents
Stereoselective Radical-Mediated Cyclization of Norephedrine Derived α-Iodoamides: Synthesis of Enantiopure Pyrrolidines and Transition State Modelling
Belvisi, Laura,Gennari, Cesare,Poli, Giovanni,Scolastico, Carlo,Salom, Barbara,Vassallo, Marco
, p. 3945 - 3960 (2007/10/02)
Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective ( 97:3) favouring diastereoisomer 2.Bicyclic lactams 2 were transformed in high yields into enantiomerically pure pyrrolidines 10.Transition stat