1430730-29-2

Upstream product

• 28819-30-9 benzohydrazonamide 
• 286369-05-9 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl cyanide 

Downstream Products

• 1430730-34-9 N-benzenecarboximidoyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)carbohydrazonoyl bromide 
• 1430730-66-7 5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-triazole 

Relevant academic research and scientific papers

GLYCOGEN PHOSPHORYLASE INHIBITORS

The invention relates to compounds of formula (I) and stereoisomers, tautomers and pharmaceutically acceptable salts thereof and processes for preparing them. In formula (I) X is -CH= or -N= or -N(R") -; Y is -N= or -N(R") -; R is an alkyl group, an aryl group or a heteroaryl group, which groups are unsubstituted or substituted; R' is hydrogen or PG1, R" is hydrogen or PG2, R"' is hydrogen or R'OCH2-; n is an integer of 1 to 3. The invention also relates to pharmaceutical compositions containing these compounds. The compounds according to the invention are glycogen phosphorylase inhibitors and can be used e.g. for the treatment of type 2 diabetes, cardiovascular disorders and tumorous growth.˙