1430737-91-9Relevant academic research and scientific papers
Highly diastereo- and enantioselective direct aldol reaction under solvent-free conditions
Zhang, Furen,Li, Chunmei,Qi, Chenze
, p. 380 - 388 (2013)
An efficient, solvent-free protocol for the asymmetric aldol reaction between aldehydes and ketones using prolinamides 1-4 as organocatalysts is reported. Catalysts 2-4, in the presence of TFA (the ratio of catalyst and TFA = 1/1.5), proved to be excellen
