1430747-34-4Relevant academic research and scientific papers
Development of Plowast-monodentate diamidophosphites with a C1-symmetric 1,2-diamine backbone: The effects of substituents in the 1,3,2-diazaphospholidine cycle on Pd-catalyzed asymmetric allylations
Gavrilov, Konstantin N.,Shiryaev, Alexei A.,Zheglov, Sergey V.,Potapova, Oksana V.,Chuchelkin, Ilya V.,Novikov, Ivan M.,Rastorguev, Eugenie A.,Davankov, Vadim A.
, p. 409 - 417 (2013/06/27)
We have designed and synthesized a small library of modular monodentate diamidophosphite ligands with stereogenic phosphorus atoms. The library was prepared efficiently from the commercially available and inexpensive (S)-N-Boc-amino acids. These novel ligands were screened in the Pd-catalyzed asymmetric allylations of (E)-1,3-diphenylallyl acetate with dimethyl malonate as the C-nucleophile with up to 93% ee being obtained. The results showed that the different substituents in the 1,3,2-diazaphospholidine cycle had remarkable effects on the enantioselectivity.
Pd-Catalyzed asymmetric transformations involving P*-mono- and P*,N-bidentate diamidophosphites derived from (2S,3S)-N 2,3-dimethyl-N 1-phenylpentane-1,2-diamine
Gavrilov,Chuchelkin,Zheglov,Shiryaev,Potapova,Novikov,Rastorguev,Davankov
, p. 1925 - 1932 (2013/12/04)
The synthesis of new P*-mono- and P*,N-bidentate diamidophosphites, containing 1,3,2-diazaphospholidine rings formed starting from (2S,3S)-N 2,3-dimethyl-N 1-phenylpentane-1,2-diamine, is described. Comparison of their efficiency in
