1430852-06-4Relevant academic research and scientific papers
Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis
Kueh, Jui Thiang Brian,Choi, Ka Wai,Williams, Geoffrey M.,Moehle, Kerstin,Bacsa, Bernadett,Robinson, John A.,Brimble, Margaret A.
supporting information, p. 3807 - 3811 (2013/04/10)
Spiropins for SPPS: The rigid structure of an anomerically stabilised spiroketal motif enables the appendage of substituents in a fixed conformation. To assess the ability of a spiroketal motif to induce a turn structure and participate in solid-phase peptide synthesis (SPPS), an Fmoc-spiroketal amino acid was synthesised and incorporated into a spiroketal-containing cyclic peptide (see figure). Copyright
