143093-29-2Relevant academic research and scientific papers
Synthesis of β-and β,β-substituted Morita-Baylis-Hillman adducts using a two-step protocol
MaGee, David I.,Ratshonka, Same,McConaghy, Jessica,Hood, Maggie
experimental part, p. 450 - 463 (2012/06/16)
The synthesis of a large number of β-and β,β-substituted keto esters was successful by the use of the Knoevenagel condensation reaction. The stereoselectivity of these reactions was improved by alteration of various substituent groups. Although there were
COBALT(II) CHLORIDE CATALYSED CONDENSATION OF ACETOACETATE WITH ENOLISABLE ALDEHYDES
Iqbal, Javed,Srivastava, Rajiv Ranjan
, p. 1663 - 1666 (2007/10/02)
Enolisable aldehydes and methyl acetoacetate react in the presence of cobalt(II) chloride (catalytic) to give the corresponding α,β-unsaturated carbonyl compound in excellent yields.Non enolisable aldehydes do not react under these conditions.A catalytic cycle for these reactions has been proposed by involving the intermediacy of a cobalt(III) enol complex of aldehydes.
