143101-25-1 Usage
Description
2-ETHYNYL-4,5-DIFLUORO-PHENYLAMINE, also known as 4,5-difluoro-2-ethynyl aniline, is a chemical compound with the molecular formula C8H5F2N. It is a substituted aniline derivative characterized by a phenyl ring with two fluorine atoms and an ethynyl group attached to the nitrogen atom. This pale yellow to brown colored solid is slightly soluble in water and has a melting point of approximately 105-107 degrees Celsius. Primarily used as an intermediate in the synthesis of various organic compounds, it plays a crucial role in the production of pharmaceuticals, agrochemicals, and other fine chemicals.
Uses
Used in Pharmaceutical Industry:
2-ETHYNYL-4,5-DIFLUORO-PHENYLAMINE is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, featuring fluorine atoms and an ethynyl group, allows for the development of new drugs with improved properties, such as enhanced potency, selectivity, and bioavailability.
Used in Agrochemical Industry:
In the agrochemical sector, 2-ETHYNYL-4,5-DIFLUORO-PHENYLAMINE serves as a vital building block in the creation of novel agrochemicals. Its incorporation into these compounds can lead to the development of more effective and targeted pesticides, herbicides, and other agricultural products.
Used in Fine Chemicals Production:
2-ETHYNYL-4,5-DIFLUORO-PHENYLAMINE is also utilized in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, such as research, specialty manufacturing, and high-value consumer products. Its unique properties make it a valuable component in the development of these specialized compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 143101-25-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,1,0 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 143101-25:
(8*1)+(7*4)+(6*3)+(5*1)+(4*0)+(3*1)+(2*2)+(1*5)=71
71 % 10 = 1
So 143101-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F2N/c1-2-5-3-6(9)7(10)4-8(5)11/h1,3-4H,11H2
143101-25-1Relevant articles and documents
New Indolo[3,2-b]indole based small organic molecules for Organic Thin Film Transistors (OTFTs): A combined experimental and DFT Study
Puli, Venkat Swamy,Subburu, Mahesh,Bhongiri, Yadagiri,Tripathi, Anuj,Prasad,Chatterjee, Anindita,Pola, Someshwar,Chetti, Prabhakar
, (2020/11/04)
Synthesis of new indolo[3,2-b]indoles (5a- 5j) in presence of Ag-doped ZnO and (Diacetoxyiodo) benzene system under visible-light have been reported. All the new fused linear heterocyclic indolo[3,2-b]indole systems (5a- 5j) thoroughly characterized by spectroscopic methods like mass, UV-visible, NMR and C, H, N elemental analysis. Further, their photophysical properties were carried out by combined experimental and theoretical studies. Thermogravimetric studies are carried out to confirm the thermal stability of molecules. The frontier molecular orbitals of molecules are characterized with the help of cyclic voltammetry. Additionally, the compounds of series 5 were used for the fabrication of organic thin-film transistors, which indicated the hole mobilities in the range of 0.11 – 0.85 cm2/Vs and with on/off ratio 105 on ODTS-SiO2 substrate at 50 °C and are also supported by DFT studies.
NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY
-
Page/Page column 47-48, (2020/01/24)
The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXRα and/or LΧΚβ) and act preferably as inverse agonists of LXR.
