143136-53-2

Usage

Appearance

Colorless liquid

Odor

Faint

Solubility

Soluble in water

Uses

Commonly used in the synthesis of pharmaceuticals and other organic compounds

Physical state

Liquid

Safety precautions

Handle with caution due to potential harm if ingested, inhaled, or absorbed through the skin

Potential hazards

May cause irritation to the eyes, skin, and respiratory system

Safety measures

Proper safety measures should be taken when working with 1,3-Dioxane-2-carboxaldehyde, 4-(methoxymethyl)- (9CI)

Chemical classification

9CI (Chemical Abstracts Service Registry Number)

Upstream product

• 90325-07-8 4-methoxybutane-1,3-diol 
• 143136-46-3 (2R,4R)-2-(Bis-ethylsulfanyl-methyl)-4-methoxymethyl-[1,3]dioxane 

Relevant academic research and scientific papers

Chiral aldehydo- and hydrazono-acetals: synthesis and diastereoselective addition of organometallics

Various cyclic chiral acetals with an adjacent aldehyde or hydrazone function were synthesized in order to study the chirality transfer during the nucleophilic addition of organometallics on the unsaturated function.Acetals of different geometry (dioxans or dioxolans) were prepared, with one or two more or less voluminous oxygenated substituents able to be involved either in chelation or in steric hindrance.Aldehydo-acetals were obtained from 2,2-diethylthioethanal and hydrazono-acetals from the 1,1-dimethylhydrazone of 2,2-dimethoxyethanal, in both cases with a transacetalization by chiral 1,2- or 1,3-diols.An excellent diastereoselectivity is observed when organolithium compounds are added to some hydrazono-acetals. Key Words: chiral cyclic acetals / aldehydo-acetals / hydrazono-acetals / organometallics / chirality transfer