143137-35-3 Usage
Uses
RS 56812 is an extremely potent and selective SR-3 partial agonist. Ligand of 5-Hydroxytryptamine (5-HT3) receptor.
Biological Activity
A highly potent and selective 5-HT 3 partial agonist, with a pK i at 5-HT 3 receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 143137-35-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,1,3 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 143137-35:
(8*1)+(7*4)+(6*3)+(5*1)+(4*3)+(3*7)+(2*3)+(1*5)=103
103 % 10 = 3
So 143137-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H21N3O2.ClH/c1-20-10-14(13-4-2-3-5-16(13)20)17(22)18(23)19-15-11-21-8-6-12(15)7-9-21;/h2-5,10,12,15H,6-9,11H2,1H3,(H,19,23);1H/t15-;/m0./s1
143137-35-3Relevant articles and documents
Serotonergic alpha-oxoacetamides
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, (2008/06/13)
α-Oxoacetamides of the formula R 1 C(O)C(O)NR 2 R 3 in which R 1 is optionally substituted phenyl, 1-indolyl, 2,3-dihydro-1-indolyl, 1-benzimidazolidinonyl, 3-benzofuranyl, 3-benzothiophenyl, 3-indolyl, and 1,2-alkano-3-indolyl; R 2 is selected from: STR1 and R 3 is selected from hydrogen or lower alkyl; and the pharmaceutically acceptable salts, individual isomers, mixtures of isomers, processes for preparation, compositions, and methods of use thereof.
