143139-14-4

Basic information

• Product Name: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER
• Synonyms: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER;3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
• CAS NO: 143139-14-4
• Molecular Formula: C₁₁H₉F₃O₃S
• Molecular Weight: 278.25
• Mol File: 143139-14-4.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(143139-14-4)
• EPA Substance Registry System: TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER(143139-14-4)

Safety Data

• Hazardous Substances Data: 143139-14-4(Hazardous Substances Data)

Usage

General Description

TRIFLUORO-METHANESULFONIC ACID 3,4-DIHYDRO-NAPHTHALEN-2-YL ESTER is a chemical compound used in various industrial applications, including as a catalyst in organic synthesis reactions. It is derived from naphthalene, a hydrocarbon compound commonly found in coal tar and crude oil. The presence of trifluoromethanesulfonic acid in the compound enhances its reactivity and stability, making it a valuable tool for chemical reactions. However, it is important to handle this compound with caution due to its potential hazards and toxicity.

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 456-64-4 phenyl trifluoromethanesulfonamide 
• 140-29-4 phenylacetonitrile 
• 100-47-0 benzonitrile 
• 104-85-8 para-methylbenzonitrile 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 38553-85-4 β-tetralone 
• 555-21-5 4-Nitrophenylacetonitrile 
• 140-53-4 p-chlorobenzyl cyanide 
• 22364-68-7 2-tolylmethylnitrile 
• 75-05-8 acetonitrile 
• 3218-49-3 3,4-dichloro-benzeneacetonitrile 

Downstream Products

• 20669-52-7 3-phenyl-1,2-dihydronaphthalene 
• 92013-27-9 3-bromo-1,2-dihydroxynaphthalene 
• 126745-32-2 1,2-dihydro-3-(phenylthio)naphthalene 
• 1449115-32-5 1-tosyl-1H-benzo[g]indole 
• 1449115-13-2 1-tosyl-4,5-dihydro-1H-benzo[g]indole 
• 1449115-43-8 4-(3,4-dihydronaphthalen-2-yl)-1-tosyl-1H-1,2,3-triazole 
• 1397263-67-0 phenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-60-5 2,6-difluorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-58-1 2,4,6-trichlorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-57-0 4-trifluoromethylphenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-56-9 4-chlorophenyl 3,4-dihydronaphthalene-2-carboxylate 
• 1402012-54-7 1,1'-biphenyl-4-yl 3,4-dihydronaphthalene-2-carboxylate 
• 1361132-12-8 1,3-dimethyl-5-(2-(1,2,3,4-tetrahydronaphthalen-2-yl)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1361132-01-5 C₁₇H₁₆O 

Relevant articles and documents

COMPOUNDS AS GLP-1R AGONISTS

The present application provides compounds that may be used as a glucagon-like peptide-1 receptors (GLP-1R) agonist, or stereoisomers, tautomers, or pharmaceutically acceptable salts of any of the foregoing. Also provided are pharmaceutical compositions containing such compounds, or stereoisomers, tautomers, or pharmaceutically acceptable salts of any of the foregoing. Methods of prepare these compounds and compositions and method of using them to treat or present a disease or a condition mediated by GLP-1R.

Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical

Direct oxidative C(sp)?H/C(sp3)?H cross-coupling offers an ideal and environmentally benign protocol for C(sp)?C(sp3) bond formations. As such, reactivity and site-selectivity with respect to C(sp3)?H bond cleavage have remained a persistent challenge. Herein is reported a simple method for iron-catalyzed/silver-mediated tertiary alkylation of terminal alkynes with readily available and versatile 1,3-dicarbonyl compounds. The reaction is suitable for an array of substrates and proceeds in a highly selective manner even employing alkanes containing other tertiary, benzylic, and C(sp3)?H bonds alpha to heteroatoms. Elaboration of the products enables the synthesis of a series of versatile building blocks. Control experiments implicate the in situ generation of a tertiary carbon-centered radical species.

A Stepwise Annulation for the Transformation of Cyclic Ketones to Fused 6 and 7-Membered Cyclic Enimines and Enones

The efficient construction of functionalized polycyclic structures is an important objective in organic synthesis. Herein, we disclose a three-step “[2 + n]” annulation method for the transformation of cyclic ketones to fused enimines and enones. The method relies on the Suzuki coupling reaction and the amide reductive alkenylation reaction. A series of fused bicyclic (6/6, 6/7, 8/7) and tricyclic (6/6/6; 6/6/7, 6/5/7) ring systems bearing an α,β-enimine or an α,β-enone functionality have been synthetized in good overall yields.