1431505-83-7

Basic information

• Product Name: (E/Z)-methyl 3-(4-tert-butoxyphenyl)-2-dimethylaminoacrylate
• Synonyms: (E/Z)-methyl 3-(4-tert-butoxyphenyl)-2-dimethylaminoacrylate
• CAS NO: 1431505-83-7
• Molecular Weight: 277.364
• Mol File: 1431505-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E/Z)-methyl 3-(4-tert-butoxyphenyl)-2-dimethylaminoacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E/Z)-methyl 3-(4-tert-butoxyphenyl)-2-dimethylaminoacrylate(1431505-83-7)
• EPA Substance Registry System: (E/Z)-methyl 3-(4-tert-butoxyphenyl)-2-dimethylaminoacrylate(1431505-83-7)

Safety Data

• Hazardous Substances Data: 1431505-83-7(Hazardous Substances Data)

Upstream product

• 7148-06-3 N,N-dimethylglycine methyl ester 
• 57699-45-3 p-tert-butoxybenzaldehyde 

Downstream Products

• 875112-20-2 3-(4-tert-butoxyphenyl)-2-oxopropanoic acid 
• 1431505-89-3 methyl 3-(4-tert-butoxyphenyl)-2-hydroxyacrylate 
• 875112-22-4 (R)-3-(4-tert-butoxyphenyl)-2-hydroxypropanoic acid 
• 1431506-02-3 (R)-methyl 3-(4-tert-butoxyphenyl)-2-pivaloyloxypropanoate 
• 1431505-95-1 (Z)-methyl 3-(4-tert-butoxyphenyl)-2-pivaloyloxyacrylate 

Relevant articles and documents

Enantioselective reduction of 3-aryl-2-oxo-propanoic acids: A comparison of enzymatic and transition-metal-catalyzed methods

Phenyllactic acids are important constituents of depsipeptides, which are a large class of natural products expressing a wide range of biological activities. Despite there being several methods for the enantioselective synthesis of α-hydroxy acids, almost no studies are available addressing the substrate selectivity of transition-metal and enzyme-catalyzed methods for the preparation of substituted phenyllactic or more general aryllactic acids. We report herein comparative results for Rh-DiPAMP (DiPAMP = 1,2-ethandiylbis[(o- methoxyphenyl)phenylphosphane]) and lactate dehydrogenase catalyzed enantioselective reductions of several 3-aryl-2-oxopropanoic acids. Phenyllactic acids are important constituents of depsipeptides, which are a large class of natural products expressing a wide range of biological activities. A comparative study of transition-metal and lactate dehydrogenase catalyzed enantioselective reductions of several 3-aryl-2-oxopropanoic acids as valuable sources for enantiomerically pure phenyllactic acids is described. Copyright