14316-87-1Relevant academic research and scientific papers
A novel and efficient synthetic route to perfluoroisobutyronitrile from perfluoroisobutyryl acid
Wang, Yi,Sun, Mengting,Gao, Zhanyang,Zou, Lilin,Zhong, Lingyu,Peng, Ruichao,Yu, Ping,Luo, Yunbai
, p. 37159 - 37164 (2018/11/26)
A novel synthetic route to perfluoroisobutyronitrile from perfluoroisobutyryl acid which has mild conditions and low toxicity is described. This study introduces detailed synthetic protocols and characterization including GC-MS, 13C NMR and 19F NMR spectroscopy of perfluoroisobutyryl acid, perfluoroisobutyryl chloride, perfluoroisobutyl amide and perfluoroisobutyronitrile. Besides, this route is superior to the established patent and shows potential application in high voltage electrical equipment.
Method for preparing heptafluorobutyl chloride from heptafluoro-2-haloalkane
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Paragraph 0029; 0031; 0034, (2018/07/30)
The invention discloses a method for preparing heptafluorobutyl chloride from heptafluoro-2-haloalkane. The reaction is divided into two steps: (1) introducing carbon dioxide into a solution A containing metal M under ultrasonic or high-pressure conditions, dropping heptafluoro-2-haloalkane, reacting at a temperature of 60-75 DEG C, acidifying the reaction solution to a pH value of being less than2 after reaction completion, and separating to remove the aqueous phase to obtain an intermediate heptafluoroisobutyric acid; (2) dropwise adding a halogenating agent into solvent-free heptafluoroisobutyric acid under nitrogen protection, stirring and reacting at a room temperature after dropping completion, raising the temperature to perform reflux reaction, observing and stopping the reaction after any gas is not produced, distilling and collecting the fraction of 50 DEG C or below, thereby obtaining the heptafluorobutyl chloride. The method disclosed by the invention has the advantages ofshort synthetic route, simple process flow and low equipment investment.
