143160-00-3

Upstream product

• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 143159-95-9 [1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-meth-(Z)-ylidene]-p-tolyl-amine 
• 143159-98-2 (3R,4S)-3-Benzyloxy-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-p-tolyl-azetidin-2-one 

Downstream Products

• 869283-91-0 Methanesulfonic acid (2S,3R)-2-((S)-1,2-dihydroxy-ethyl)-4-oxo-1-p-tolyl-azetidin-3-yl ester 
• 869284-00-4 Methanesulfonic acid (2S,3R)-2-hydroxymethyl-4-oxo-1-p-tolyl-azetidin-3-yl ester 
• 869283-97-6 Methanesulfonic acid (2R,3R)-2-formyl-4-oxo-1-p-tolyl-azetidin-3-yl ester 

Relevant academic research and scientific papers

Stereospecific novel glycosylation of hydroxy β-lactams via iodine-catalyzed reaction: A new method for optical resolution

Glycosylation of racemic and optically active α-hydroxy β-lactams by reaction with a few glycal derivatives in the presence of catalytic amounts of iodine has provided stereospecific formation of α-glycosides. This method has been extended for the prepara

An efficient synthesis of 2,3-aziridino-γ-lactones from azetidin-2-ones

An efficient synthesis of enantiopure 2,3-aziridino-γ-lactones from azetidin-2-ones is described. Acid-catalyzed tandem intramolecular azetidinone ring opening followed by aziridine ring formation via elimination of a mesylate group is the key step in thi

MICROWAVE-INDUCED ORGANIC REACTION ENHANCEMENT CHEMISTRY. 4 CONVENIENT SYNTHESIS OF ENANTIOPURE α-HYDROXY-β-LACTAMS

A convenient and rapid synthesis of enantiopure α-hydroxy-β-lactams using microwave-induced organic reaction enhancement chemistry has been developed.Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or teaching laboratories, can also be conducted on a preparative scale of 100 - 500 g in simple beakers or flasks. Key Words: α-Hydroxy-β-lactams, microwave-induced organic reactions, enantiospecific synthesis