143160-01-4Relevant academic research and scientific papers
An Expeditious Route for the Synthesis of Oxazepine Triazolo-β-Lactams through Intramolecular Metal-Free [3 + 2] Azide-Alkyne Cycloaddition
Yadav, Ram N.,Chandra, Sunena,Paniagua, Armando,Hossain, Md. Firoj,Banik, Bimal Krishna
, p. 654 - 657 (2020/05/25)
A copper-free intramolecular azide-alkyne cycloaddition reaction of 4-hydroxymethyl-β-lactam with sodium azide has been described. The present approach involves the incorporation of an alkyne moiety through O-alkynylation of 3-hydroxy β-lactam with variou
Stereospecific novel glycosylation of hydroxy β-lactams via iodine-catalyzed reaction: A new method for optical resolution
Banik, Bimal K.,Manhas, Maghar S.
, p. 10769 - 10779 (2013/01/15)
Glycosylation of racemic and optically active α-hydroxy β-lactams by reaction with a few glycal derivatives in the presence of catalytic amounts of iodine has provided stereospecific formation of α-glycosides. This method has been extended for the prepara
MICROWAVE-INDUCED ORGANIC REACTION ENHANCEMENT CHEMISTRY. 4 CONVENIENT SYNTHESIS OF ENANTIOPURE α-HYDROXY-β-LACTAMS
Banik, Bimal K.,Manhas, Maghar S.,Kaluza, Zbignew,Barakat, Khaled J.,Bose, Ajay K.
, p. 3603 - 3606 (2007/10/02)
A convenient and rapid synthesis of enantiopure α-hydroxy-β-lactams using microwave-induced organic reaction enhancement chemistry has been developed.Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or teaching laboratories, can also be conducted on a preparative scale of 100 - 500 g in simple beakers or flasks. Key Words: α-Hydroxy-β-lactams, microwave-induced organic reactions, enantiospecific synthesis
