1431640-66-2Relevant academic research and scientific papers
Synthesis and insecticidal activities: Cis-nitenpyram analogs with 1,4-dihydropyridine scaffold
Liu, Tian-Yan,Xue, Si-Jia,Chen, Yan-Xia,Fang, Ting,Wu, Ying,Wang, Jing
, p. 1376 - 1379 (2012)
By means of multicomponent reactions, via Michael addition, nucleophilic addition, using nitenpyram, substituted aromatic aldehydes, and cyanoacetate compounds or propanedinitrile, a new series of cis-configuration nitenpyram analogs (1a-1k) were synthesized by introducing the 1,4-dihydropyridine scaffold pharmacophore, as shown in Scheme 1. The structures of all compounds were confirmed by IR, 1HNMR, 13C NMR, and elemental analysis. The preliminary bioassay showed that most of the target compounds exhibited good mortality against Aphis craccivora at 500 mg/L.
