1431641-97-2Relevant academic research and scientific papers
A rational approach towards a new ferrocenyl pyrrolidine for stereoselective enamine catalysis
Petruzziello, Diego,Stenta, Marco,Mazzanti, Andrea,Cozzi, Pier Giorgio
, p. 7696 - 7700 (2013)
Ironing out the details: Proline and pyrrolidine derivatives (Hayashi- J?rgensen catalysts) are considered work horses in organocatalysis. This report describes a new effective ferrocenyl pyrrolidine catalyst that is able to perform well in benchmark organocatalytic reactions (see figure). The ferrocene moiety controls the conformational space and a simple alkyl group effectively covers a face of the derived enamine. This new framework can find applications in organocatalysis, and in general, in new ligand design. Copyright
