1431642-42-0

Basic information

• Product Name: C₂₄H₂₉N₃O₅S
• CAS NO: 1431642-42-0
• Molecular Weight: 471.577
• Mol File: 1431642-42-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₉N₃O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₉N₃O₅S(1431642-42-0)
• EPA Substance Registry System: C₂₄H₂₉N₃O₅S(1431642-42-0)

Safety Data

• Hazardous Substances Data: 1431642-42-0(Hazardous Substances Data)

Upstream product

• 104504-02-1 4-methyl-N-(tosyloxy)benzenesulfonamide 
• 1431642-20-4 C₁₇H₂₂N₂O₃ 
• 1296698-40-2 (S)-di-tert-butyl 1-(1-oxo-2-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate 
• 870-50-8 di-tert-butyl-diazodicarboxylate 
• 34713-70-7 2-Phenylpropanal 

Relevant articles and documents

Enantioselective organocatalytic one-pot amination/aza-Michael/aldol condensation reaction sequence: Synthesis of 3-pyrrolines with a quaternary stereocenter

Primary amine-catalyzed direct conversion of α,α-disubstituted aldehydes into 3-pyrrolines with a quaternary stereocenter is reported. The one-pot enantioselective sequence is based on a α-amination, an aza-Michael addition of hydrazine, an aldol condensation dehydratation and proceeds with good yields and excellent levels of enantioselectivity. Synthetically attractive applications including the formation of aziridinopyrrolidine or epoxypyrrolidine derivatives with good yields and selectivities are also described. Expect the unexpected: Primary amine-catalyzed direct conversion of α,α-disubstituted aldehydes into 3-pyrrolines with a quaternary stereocenter is reported. The sequence involves an α-amination, an aza-Michael addition of hydrazine, an aldol condensation and proceeds with good yields and excellent levels of enantioselectivity (see scheme). Copyright