1431697-74-3
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Basic information
- Product Name: CAL 130
- Synonyms: CAL130; CAL 130;4(3H)-Quinazolinone, 2-[(1S)-1-[(2-amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-
- CAS NO:1431697-74-3
- Molecular Formula: C23H22N8O
- Molecular Weight: 426.47378
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1431697-74-3.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: CAL 130(CAS DataBase Reference)
- NIST Chemistry Reference: CAL 130(1431697-74-3)
- EPA Substance Registry System: CAL 130(1431697-74-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1431697-74-3(Hazardous Substances Data)
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1431697-74-3 Usage
Chemical class
Complex organic compoundCore structure
QuinazolineSide chains
Purine and methylphenylDerivative
QuinazolinonePotential activities
Antineoplastic and antiangiogenicMechanism of action
Inhibition of tyrosine kinase phosphorylationEffect on signaling pathways
Inhibition of Ras/Raf/MEK/ERK pathwayOutcomes
Inhibition of tumor cell proliferation, induction of tumor cell apoptosisAdditional targets
Inhibition of VEGFR-1 and VEGFR-2 tyrosine kinases (vascular endothelial growth factor receptor)Further research
Needed to understand potential uses and effectsCheck Digit Verification of cas no
The CAS Registry Mumber 1431697-74-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,1,6,9 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.Calculate Digit Verification of CAS Registry Number 1431697-74:
(9*1)+(8*4)+(7*3)+(6*1)+(5*6)+(4*9)+(3*7)+(2*7)+(1*4)=173
173 % 10 = 3
So 1431697-74-3 is a valid CAS Registry Number.
1431697-74-3Upstream product
1431697-74-3Downstream Products
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CAL 130
