143184-61-6Relevant articles and documents
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir
Eriksson, Ulrika,Hilfinger, John M.,Kim, Jae-Seung,Mitchell, Stefanie,Kijek, Paul,Borysko, Katherine Z.,Breitenbach, Julie M.,Drach, John C.,Kashemirov, Boris A.,McKenna, Charles E.
, p. 583 - 586 (2007)
Cidofovir (HPMPC) is a broad-spectrum anti-viral agent whose potential, particularly in biodefense scenarios, is limited by its low oral bioavailability. Two prodrugs (3 and 4) created by conjugating ethylene glycol-linked amino acids (L-Val, L-Phe) with
