143185-43-7

Basic information

• Product Name: 2-(2-N-BOC-AMINOETHYL) PYRIDINE
• Synonyms: 2-(2-N-BOC-AMINOETHYL) PYRIDINE;tert-Butyl 2-pyridin-2-ylethylcarbamate
• CAS NO: 143185-43-7
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28
• Mol File: 143185-43-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 346.7°Cat760mmHg
• Flash Point: 163.5°C
• Appearance: /
• Density: 1.056g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: 2-(2-N-BOC-AMINOETHYL) PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-N-BOC-AMINOETHYL) PYRIDINE(143185-43-7)
• EPA Substance Registry System: 2-(2-N-BOC-AMINOETHYL) PYRIDINE(143185-43-7)

Safety Data

• Hazardous Substances Data: 143185-43-7(Hazardous Substances Data)

Usage

Derived from

Pyridine

Functional group

BOC (tert-butoxycarbonyl) protecting group attached to the amino group

Usage

Building block in organic synthesis

Applications

Production of pharmaceuticals, agrochemicals, materials science, and catalysis

Importance

Versatile and widely used chemical reagent in various industries

InChI:InChI=1/C12H18N2O2/c1-12(2,3)16-11(15)14-9-7-10-6-4-5-8-13-10/h4-6,8H,7,9H2,1-3H3,(H,14,15)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 7150-72-3 t-butyl N-vinylcarbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1321892-09-4 N-formyl-N-vinyl-carbamic acid tert-butyl ester 
• 2706-56-1 2-(aminoethyl)pyridine 
• 100-71-0 2-Ethylpyridine 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 

Downstream Products

• 501377-01-1 N-[2-[6-(4-Oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]ethyl]benzamide 
• 248607-68-3 2-(2-tert-butoxycarbonylaminoethyl)-1-(3,4-dichlorobenzyl)pyridium bromide 
• 144164-08-9 (S)-3-Methyl-2-[3-methyl-3-(2-pyridin-2-yl-ethyl)-ureido]-butyric acid 4-nitro-phenyl ester 
• 5638-76-6 betahistine 
• 885954-19-8 tert-butyl N-[2-(piperidin-2-yl)ethyl]carbamate 

Relevant articles and documents

Catalytic Strategy for Regioselective Arylethylamine Synthesis

A mild, modular, and practical catalytic system for the synthesis of the highly privileged phenethylamine pharmacophore is reported. Using a unique combination of organic catalysts to promote the transfer of electrons and hydrogen atoms, this system performs direct hydroarylation of vinyl amine derivatives with a wide range of aryl halides (including aryl chlorides). This general and highly chemoselective protocol delivers a broad range of arylethylamine products with complete regiocontrol. The utility of this process is highlighted by its scalability and the modular synthesis of an array of bioactive small molecules.

INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES

Disclosure is provided for carbamate compounds that prevent, remove and/or inhibit the formation of biofilms, compositions including these compounds, devices including these compounds, and methods of using the same.

Quinolones used as MRS inhibitors and bactericides

Compounds of formula (I) are inhibitors of the bacterial enzymeS aureusmethionyl tRNA synthetase and are of use in treating bacterial infections.