1431927-80-8

Basic information

• Product Name: dimethyl 4-(2-amino-1-cyano-2-oxoethyl)-1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrole-2,3-dicarboxylate
• CAS NO: 1431927-80-8
• Molecular Weight: 457.894
• Mol File: 1431927-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 4-(2-amino-1-cyano-2-oxoethyl)-1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrole-2,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 4-(2-amino-1-cyano-2-oxoethyl)-1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrole-2,3-dicarboxylate(1431927-80-8)
• EPA Substance Registry System: dimethyl 4-(2-amino-1-cyano-2-oxoethyl)-1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrole-2,3-dicarboxylate(1431927-80-8)

Safety Data

• Hazardous Substances Data: 1431927-80-8(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 138380-43-5 2-thiopheneglyoxal monohydrate 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 109-77-3 malononitrile 

Relevant articles and documents

Highly efficient synthesis of polysubstituted pyrroles via four-component domino reaction

A highly efficient, catalyst-free synthesis of polysubstituted pyrroles by means of a novel four-component domino reaction of an arylglyoxal monohydrate, an aniline, a dialkyl but-2-ynedioate, and malononitrile is reported. This transformation proceeded via a 6,6a-dihydrofuro[2,3-b]pyrrole as the key intermediate.