1431986-45-6Relevant articles and documents
Regiospecific synthesis of 1,5,6,7-tetrahydro-4H-indol-4-ones via dehydroxylated [3+2] cyclization of β-hydroxy ketones with cyclic enaminones
Lan, Xin-Chan,Chen, Ting-Ting,Zhao, Yan,Wu, Yu,Wang, Jing,Tu, Shu-Jiang,Jiang, Bo,Hao, Wen-Juan
, p. 1519 - 1522 (2017)
A new p-TsOH-promoted dehydroxylated [3+2] cyclization strategy has been established, allowing a flexible, practical and regiospecific approach to 23 examples of 1,5,6,7-tetrahydro-4H-indol-4-ones from low-cost and readily accessible β-hydroxy ketones and cyclic enaminones. Notably features of this work include broad functional group compatibility, mild reaction conditions and good reaction yields.