143209-53-4Relevant academic research and scientific papers
Novel 3,3-disubstituted oxindole derivatives. Synthesis and evaluation of the anti-proliferative activity
Christodoulou, Michael S.,Nicoletti, Ferdinando,Mangano, Katia,Chiacchio, Maria Assunta,Facchetti, Giorgio,Rimoldi, Isabella,Beccalli, Egle M.,Giofrè, Sabrina
, (2019/12/24)
3,3-Disubstituted oxindole derivatives bearing a nitrogen atom at the C-3 position have been synthesized starting from 3-alkyl oxindole through a metal free pathway. These derivatives have been tested in five human tumor cell lines (PC3, MCF7, SW620, MiaP
Synthesis of pyrrolo[1,2-c]quinazoline derivatives
Beccalli, Egle M.,Marchesini, Alessandro,Pilati, Tullio
, p. 5359 - 5374 (2007/10/02)
Δ2-Pyrrolin-4-ones 12 and 13, prepared from 1-acyl-3-alkyl-1,3-dihydro-2H-indol-2-ones 1, via the corresponding 3-bromo-, 2 and 6, 3-azido, 7 and 8, and 3-iminophosphorane 9 and 10, were cyclized to the corresponding pyrrolo[1,2-c]quinazoline d
