1432503-06-4Relevant academic research and scientific papers
Efficient access to fluorinated homoallylic alcohols through an indium promoted fluoroallylation reaction
Lemonnier, Gérald,Van Hijfte, Nathalie,Sebban, Muriel,Poisson, Thomas,Couve-Bonnaire, Samuel,Pannecoucke, Xavier
, p. 3123 - 3133 (2014/05/06)
Herein, an efficient access to fluorinated homoallylic alcohol is reported. The fluorinated alcohols were obtained in good to excellent yield using indium and halo-fluorinated allylic derivatives. The developed methodology using γ-substituted halo-fluorin
A practical and straightforward access to fluorinated homoallylic alcohols in aqueous media
Lemonnier, Gérald,Poisson, Thomas,Couve-Bonnaire, Samuel,Pannecoucke, Xavier
, p. 2821 - 2824 (2013/06/05)
Herein, a practical and straightforward access to fluorinated homoallylic alcohols is reported. The corresponding products were obtained in good to excellent yield in brine or THF as a solvent using indium(0) and the readily available 3-chloro-2-fluoroprop-1-ene to promote the allylation reaction. This methodology affords an easy access to valuable fluorinated products under mild conditions.
