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1432511-70-0

(+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1432511-70-0 Structure

  • Basic information

    1. Product Name: (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine
    2. Synonyms: (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine
    3. CAS NO:1432511-70-0
    4. Molecular Formula:
    5. Molecular Weight: 249.208
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1432511-70-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine(1432511-70-0)
    11. EPA Substance Registry System: (+)-(3S,5S)-3-(2-fluorophenyl)-3-methyl-5-trifluoromethylisoxazolidine(1432511-70-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1432511-70-0(Hazardous Substances Data)

1432511-70-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1432511-70-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,2,5,1 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1432511-70:
(9*1)+(8*4)+(7*3)+(6*2)+(5*5)+(4*1)+(3*1)+(2*7)+(1*0)=120
120 % 10 = 0
So 1432511-70-0 is a valid CAS Registry Number.

1432511-70-0Upstream product

1432511-70-0Relevant articles and documents

β-secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease

Hilpert, Hans,Guba, Wolfgang,Woltering, Thomas J.,Wostl, Wolfgang,Pinard, Emmanuel,Mauser, Harald,Mayweg, Alexander V.,Rogers-Evans, Mark,Humm, Roland,Krummenacher, Daniela,Muser, Thorsten,Schnider, Christian,Jacobsen, Helmut,Ozmen, Laurence,Bergadano, Alessandra,Banner, David W.,Hochstrasser, Remo,Kuglstatter, Andreas,David-Pierson, Pascale,Fischer, Holger,Polara, Alessandra,Narquizian, Robert

, p. 3980 - 3995 (2013/06/27)

An extensive fluorine scan of 1,3-oxazines revealed the power of fluorine(s) to lower the pKa and thereby dramatically change the pharmacological profile of this class of BACE1 inhibitors. The CF3 substituted oxazine 89, a potent and

FLUOROMETHYL-5,6-DIHYDRO-4H-[1,3]OXAZINES

-

Page/Page column 48, (2013/08/15)

The present invention provides a compound of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease

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