1432576-76-5

Basic information

• Product Name: (S)-benzyl 2-((S)-1-((S)-1-tert-butoxy-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate
• Synonyms: (S)-benzyl 2-((S)-1-((S)-1-tert-butoxy-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate
• CAS NO: 1432576-76-5
• Molecular Weight: 475.585
• Mol File: 1432576-76-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-benzyl 2-((S)-1-((S)-1-tert-butoxy-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-benzyl 2-((S)-1-((S)-1-tert-butoxy-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate(1432576-76-5)
• EPA Substance Registry System: (S)-benzyl 2-((S)-1-((S)-1-tert-butoxy-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate(1432576-76-5)

Safety Data

• Hazardous Substances Data: 1432576-76-5(Hazardous Substances Data)

Upstream product

• 26061-29-0 (S)-benzyl 2-((S)-1-tert-butoxy-3-methyl-1-oxobutan-2-ylcarbamoyl)pyrrolidine-1-carboxylate 
• 13211-31-9 tert-butyl L-valinate 
• 21691-50-9 Ala-OtBu 

Relevant articles and documents

Amide formation in one pot from carboxylic acids and amines via carboxyl and sulfinyl mixed anhydrides

An efficient method has been developed for the preparation of yet unknown acyclic mixed anhydrides of carboxylic and sulfinic acids. Sterically hindered 2-methylbut-3-ene-2-sulfinyl carboxylates add primary and secondary amines preferentially onto the carbonyl moieties realizing a new method for the one-pot preparation of carboxamides. It uses 1:1 mixtures of carboxylic acids and amines without a base, requires no excess of reagents, and liberates only volatile coproducts. Protected di- and tripeptides have been prepared in solution without epimerization by application of this method.