1432591-75-7 Usage
Chemical structure
A complex structure derived from glucose, with modifications to the hydroxyl groups and a cyclic six-membered ring.
Hydroxyl group protection
The hydroxyl groups at the 2 and 4 positions are protected by tert-butyldiphenylsilyl groups, which prevent unwanted reactions at these sites.
1,6-anhydro ring structure
The compound is missing an oxygen atom at the 1st carbon position, resulting in a cyclic six-membered ring.
Derivative of glucose
It is a modified version of the simple sugar glucose, which is a common building block in organic chemistry.
Organic synthesis
The compound is commonly used in organic synthesis as a building block for creating more complex molecules.
Selective and controlled modifications
The protected hydroxyl groups allow for selective and controlled modifications, which is important for the synthesis of specific target molecules.
Carbohydrate chemistry
The compound's unique structure and reactivity make it a valuable tool in carbohydrate chemistry, a field focused on the study and manipulation of carbohydrates.
Pharmaceutical production
It is used in the production of pharmaceuticals, as its controlled reactivity can be harnessed to create specific drug molecules.
Advanced materials
The compound can also be used in the production of advanced materials, such as polymers and other complex structures with unique properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1432591-75-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,2,5,9 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1432591-75:
(9*1)+(8*4)+(7*3)+(6*2)+(5*5)+(4*9)+(3*1)+(2*7)+(1*5)=157
157 % 10 = 7
So 1432591-75-7 is a valid CAS Registry Number.
1432591-75-7Relevant articles and documents
β-Selective C-arylation of silyl protected 1,6-anhydroglucose with arylalanes: The synthesis of SGLT2 inhibitors
Henschke, Julian P.,Wu, Ping-Yu,Lin, Chen-Wei,Chen, Shi-Feng,Chiang, Pei-Chen,Hsiao, Chi-Nung
, p. 2295 - 2309 (2015)
The stereoselective arylation of hydroxy protected 1,6-anhydro-β-d-glucose with arylalanes to provide β-C-arylglucosides is reported. Modification of triarylalanes, Ar3Al, with strong Br?nsted acids (HX) or AlCl3 produced more reactive arylating agents, Ar2AlX, while the incorporation of alkyl dummy ligands into the arylating agents was also viable. Me3Al and i-Bu2AlH were found useful in the in situ blocking of the C3-hydroxyl group of 2,4-di-O-TBDPS protected 1,6-anhydroglucose. The utility of the method was demonstrated by the synthesis of the SGLT2 inhibitor, canagliflozin.
