143261-31-8

Upstream product

• 143261-30-7 (Z)-7-[(1R,2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-2-(methoxy-phenylsulfanyl-methyl)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 64493-06-7 methyl (5Z)-7-iodo-5-heptenoate 
• 87262-37-1 lithium 
• 143261-29-4 (Z)-7-[(1R,2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-methyl)-5-oxo-cyclopentyl]-hept-5-enoic acid methyl ester 
• 143261-28-3 (Z)-7-[(1R,2R,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-(methoxy-phenylsulfanyl-trimethylsilanyl-methyl)-5-oxo-cyclopentyl]-hept-5-enoic acid methyl ester 
• 61305-35-9 (R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone 

Downstream Products

• 61218-06-2 methyl (Z)-7-[(1R,2R,3R,5S)-5-acetoxy-2-formyl-3-(2-tetrahydropyranyloxy)cyclopentyl]-5-heptenate 
• 143261-33-0 (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-2-(methoxy-phenylsulfanyl-methyl)-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 143261-32-9 (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-hydroxy-2-(methoxy-phenylsulfanyl-methyl)-cyclopentyl]-hept-5-enoic acid methyl ester 

Relevant academic research and scientific papers

A Divergent Entry into Prostaglandin Synthesis through 1,4-Addition of Methoxy(phenylthio)(trimethylsilyl)methyllithium to 4-Siloxy-2-cyclopentenone

1,4-Addition of methoxy(phenylthio)(trimethylsilyl)methyllithium to 4-siloxy-2-cyclopentenone followed by in situ alkylation of the resulting enolate provides a versatile intermediate for synthesis of prostaglandins.