1432610-47-3Relevant academic research and scientific papers
Pd-catalyzed one-pot synthesis of polysubstituted acrylamidines from isocyanides, diazo compounds, and imines
Yan, Xu,Liao, Jinxi,Lu, Yongzhi,Liu, Jinsong,Zeng, Youlin,Cai, Qian
supporting information, p. 2478 - 2481 (2013/06/26)
A novel and efficient Pd-catalyzed one-pot reaction of ethyl diazoacetate, isocyanides, and imines for the synthesis of acrylamidines was developed. The multicomponent reaction may have occurred through an unpredicted ring-opening process of the ketenimine-imine [2 + 2] intermediate to form the acrylamidine products.
