1432629-29-2Relevant academic research and scientific papers
Pd(II)-catalyzed intramolecular aminopalladation/direct C-H arylation under aerobic conditions: Synthesis of pyrrolo[1,2-a]indoles
Piou, Tiffany,Neuville, Luc,Zhu, Jieping
supporting information, p. 4415 - 4420 (2013/06/27)
Heating a DMA/pivalic acid (v/v=4/1) solution of diversely substituted 6-(phenylamino)hex-2-ynoates in the presence of a catalytic amount of Pd(OAc)2 under oxygen atmosphere afforded pyrrolo[1,2-a]indoles in moderate to good yields. A domino sequence involving intramolecular aminopalladation followed by C-H activation and reductive elimination was proposed to account for the observed bis-cyclization.
