143268-79-5Relevant articles and documents
Novel pyridyl substituted 4,5-dihydro-[1,2,4]triazolo[4,3-a ]quinolines as potent and selective aldosterone synthase inhibitors with improved in vitro metabolic stability
Hu, Qingzhong,Yin, Lina,Ali, Amjad,Cooke, Andrew J.,Bennett, Jonathan,Ratcliffe, Paul,Lo, Michael Man-Chu,Metzger, Edward,Hoyt, Scott,Hartmann, Rolf W.
supporting information, p. 2530 - 2537 (2015/03/30)
CYP11B2 inhibition is a promising treatment for diseases caused by excessive aldosterone. To improve the metabolic stability in human liver miscrosomes of previously reported CYP11B2 inhibitors, modifications were performed via a combination of ligand-and
NEW BICYCLIC DIHYDROQUINOLINE-2-ONE DERIVATIVES
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Paragraph 0374; 0375, (2013/04/10)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12/
NEW BICYCLIC DIHYDROQUINOLINE-2-ONE DERIVATIVES
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Page/Page column 74, (2013/04/10)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4? R5, R6, R7, R8, R9, R10, R11, R12/