1432906-15-4Relevant articles and documents
NIS-catalyzed reactions: Amidation of acetophenones and oxidative amination of propiophenones
Lamani, Manjunath,Prabhu, Kandikere Ramaiah
, p. 14638 - 14642 (2012)
Single-step amination: The N-iodosuccinimide (NIS)-catalyzed amidation of acetophenone derivatives by using tert-butylhydroperoxide (TBHP) as an oxidant is presented. A variety of acetyl derivatives of heterocyclic compounds were easily converted to their corresponding ketoamides under these conditions. A new, NIS-catalyzed amination of propiophenone and its derivatives in the presence of TBHP to furnish the corresponding 2-aminoketone derivatives is the first reported single-step amination of propiophenone derivatives. Copyright