1433-82-5

Basic information

• Product Name: 3-β-azido-5-cholestene
• Synonyms: 3-β-azido-5-cholestene
• CAS NO: 1433-82-5
• Molecular Weight: 411.674
• Mol File: 1433-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-β-azido-5-cholestene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-β-azido-5-cholestene(1433-82-5)
• EPA Substance Registry System: 3-β-azido-5-cholestene(1433-82-5)

Safety Data

• Hazardous Substances Data: 1433-82-5(Hazardous Substances Data)

Upstream product

• 3381-54-2 cholesterol mesylate 

Downstream Products

• 1357271-66-9 C₃₅H₅₁N₃ 
• 2126-93-4 cholest-5-en-3-amine 
• 828293-37-4 N-[3-({3-[(3-{(3β)-cholest-5-en-3-yl[(2-nitrophenyl)sulfonyl]amino}propyl)amino]-3-oxopropyl}amino)-3-oxopropyl]-6-(7-nitrobenzofurazan-4-ylamino)hexanamide 
• 828293-23-8 N-[3-({3-[(3-{(3β)-cholest-5-en-3-yl[(2-nitrophenyl)sulfonyl]amino}propyl)amino]-3-oxopropyl}amino)-3-oxopropyl]-6-[(2,4-dinitrophenyl)amino]hexanamide 
• 828293-42-1 N-{3-[(3-{(3β)-cholest-5-en-3-yl[(2-nitrophenyl)sulfonyl]amino}propyl)amino]-3-oxopropyl}-6-(7-nitrobenzofurazan-4-ylamino)hexanamide 
• 828293-27-2 N-{3-[(3-{(3β)-cholest-5-en-3-yl[(2-nitrophenyl)sulfonyl]amino}propyl)amino]-3-oxopropyl}-6-[(2,4-dinitrophenyl)amino]hexanamide 

Relevant articles and documents

Practical synthesis of 3β-amino-5-cholestene and related 3β-halides involving i-steroid and retro-i-steroid rearrangements

(Equation Presented) Derivatives of 3β-amino-5-cholestene (3β-cholesterylamine) are of substantial interest as cellular probes and have potential medicinal applications. However, existing syntheses of 3β-amino-5-cholestene are of limited preparative utility. We report here a practical method for the stereoselective preparation of 3β-amino-5- cholestene, 3β-chloro-5-cholestene, 3β-bromo-5-cholestene, and 3β-iodo-5-cholestene from inexpensive cholesterol. A sequential i-steroid/retro-i-steroid rearrangement promoted by boron trifluoride etherate and trimethylsilyl azide converted cholest-5-en-3β-ol methanesulfonate to 3β-azido-cholest-5-ene with retention of configuration in 93% yield.