1433184-96-3Relevant academic research and scientific papers
Gold(I)-catalyzed macrocyclization of 1, n-enynes
Obradors, Carla,Leboeuf, David,Aydin, Juhanes,Echavarren, Antonio M.
supporting information, p. 1576 - 1579 (2013/06/26)
The gold(I)-catalyzed [2 + 2] cycloaddition of large 1,n-enynes (n = 10-16) provides access to 9- to 15-membered ring macrocycles incorporating a cyclobutene moiety. The reaction requires the use of a gold(I) catalyst bearing a sterically hindered biphenylphosphine ligand.
