143328-16-9

Basic information

• Product Name: 1-(3-CHLOROPHENYL)-1-CYCLOPENTANECARBONITRILE
• Synonyms: 1-(3-CHLOROPHENYL)-1-CYCLOPENTANECARBONITRILE;1-(3-Chlorophenyl)-1-cyclopentanecarbonitrile 1GR
• CAS NO: 143328-16-9
• Molecular Formula: C₁₂H₁₂ClN
• Molecular Weight: 205.68
• Mol File: 143328-16-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-CHLOROPHENYL)-1-CYCLOPENTANECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-CHLOROPHENYL)-1-CYCLOPENTANECARBONITRILE(143328-16-9)
• EPA Substance Registry System: 1-(3-CHLOROPHENYL)-1-CYCLOPENTANECARBONITRILE(143328-16-9)

Safety Data

• Hazardous Substances Data: 143328-16-9(Hazardous Substances Data)

Usage

Chemical Properties

Brown low melting mass

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 1529-41-5 3-chloro-benzeneacetonitrile 

Downstream Products

• 143328-21-6 1-(3-chlorophenyl)cyclopentanecarboxylic acid 
• 143328-26-1 1-(3-chlorophenyl)cyclopentane-1-carboxylic acid chloride 
• 143407-68-5 Sodium; (2S,5R,6R)-6-{[1-(3-chloro-phenyl)-cyclopentanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 143407-72-1 Sodium; (6R,7R)-7-{[1-(3-chloro-phenyl)-cyclopentanecarbonyl]-amino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 143407-76-5 Sodium; (6R,7R)-3-acetoxymethyl-7-{[1-(3-chloro-phenyl)-cyclopentanecarbonyl]-amino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate 

Relevant articles and documents

Amide compound and derivative thereof, preparation method, pharmaceutical composition and application thereof

The invention discloses an amide compound and derivative thereof, a preparation method, a pharmaceutical composition and application thereof. The structure of the amide compound is shown as a formula (I). The derivatives of theamide compound relate to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the above of theamide compound. The amide compound and the derivative thereof have an efficient inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing medicines for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, the prepared medicine can exert the medicine effect at the molecular level and is wide in application, and the synthesis method of the compound is simple, convenient and easy to operate.