14333-94-9

Basic information

• Product Name: Benzeneacetaldehyde, 4-butyl-a-oxo-
• CAS NO: 14333-94-9
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol File: 14333-94-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, 4-butyl-a-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, 4-butyl-a-oxo-(14333-94-9)
• EPA Substance Registry System: Benzeneacetaldehyde, 4-butyl-a-oxo-(14333-94-9)

Safety Data

• Hazardous Substances Data: 14333-94-9(Hazardous Substances Data)

Upstream product

• 104-51-8 1-butylbenzene 
• 37920-25-5 1-(4-butylphenyl)ethanone 

Downstream Products

• 94775-69-6 1-(4-Butyl-phenyl)-2-hydroxy-heptane-1,4-dione 
• 94775-78-7 3-(4-Butyl-phenyl)-6-propyl-pyridazine 
• 94775-60-7 Potassium; 2-[2-(4-butyl-phenyl)-1-hydroxy-2-oxo-ethyl]-3-oxo-hexanoate 

Relevant articles and documents

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

We report an unprecedented organocatalytic enantioselective acyloin rearrangement of α,α-disubstituted α-hydroxy acetals. In the presence of a catalytic amount of chiral binol-derived N-triflyl phosphoramide, α-hydroxy acetals rearranged to α-alkoxy ketones in good to high yields with high enantioselectivities. Formation of an ion pair between the in situ generated oxocarbenium ion and the chiral phosphoramide anion was proposed to be responsible for the highly efficient transfer of chirality. Conditions for removal of cyclohexyl and cyclopentyl groups from the corresponding α-alkoxy ketones were uncovered underpinning their potential general utility as hydroxy protecting groups. Conversion of the rearranged products to the enantioenriched α-hydroxy ketone, 1,2-diol, β-amino alcohol and 1,4-dioxane was also documented.